e-Drug3D

1975

PRETOMANID

INN
PRETOMANID

cas 187235-37-6

CLASS

ANTIINFECTIVES
NITROIMIDAZOOXAZINE ANTIMYCOBACTERIAL DRUG
TREATMENT OF ADULTS WITH PULMONARY EXTENSIVELY DRUG RESISTANT (XDR) TREATMENT-INTOLERANT OR NONRESPONSIVE MULTIDRUG-RESISTANT (MDR) TUBERCULOSIS (TB)
INHIBITING MYCOLIC ACID BIOSYNTHESIS

ROUTE (list)

ORAL

ATC code

J04AK08

PK parameters

Tmax 5 HOUR
VD 97 LITER
Cl 3.9 LITER / HOUR
PPB 86.4 PERCENT
t1/2 17.4 HOUR

Target

DrugCentral

Unknown

Download SDF file

5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-, (6S)-

Formula:
C14H12F3N3O5

Calculated chemical properties:

MW 359.27
NB_atoms 25
XLogP 2.67
PSA 89.173
NB_HD 0
NB_HA 7
fsp3 0.36
Lipinski(0=no;1=yes) 1

FDA
NDA 212862 (label) INN (PRETOMANID) PRETOMANID (MYLAN IRELAND LTD) APPROVAL= AP YEAR= 2019