e-Drug3D

1974

CENOBAMATE

INN
CENOBAMATE

cas 913088-80-9

CLASS

NERVOUS SYSTEM
TREATMENT OF PARTIAL-ONSET SEIZURES
INHIBITS VOLTAGE-GATED SODIUM CURRENTS
POSITIVE ALLOSTERIC MODULATOR OF THE GAMMA-AMINOBUTYRIC ACID (GABAA) ION CHANNEL

ROUTE (list)

ORAL

ATC code

N03AX25

PK parameters

F 88 PERCENT
Tmax 2.5 HOUR
VD 45 LITER
Cl 0.54 LITER / HOUR
PPB 60 PERCENT
t1/2 55 HOUR

Solubility

VERY SOLUBLE IN AQUEOUS SOLUTIONS (1.7 MILLIGRAM PER MILLILITER)

Target

DrugCentral

Gamma-aminobutyric acid receptor subunit alpha-4 UNIPROT P48169 GABRA4

Download SDF file

2H-Tetrazole-2-ethanol, alpha-(2-chlorophenyl)-, 2-carbamate, (alphaR)-

Formula:
C10H10ClN5O2

Calculated chemical properties:

MW 267.68
NB_atoms 18
XLogP 1.16
PSA 91.752
NB_HD 2
NB_HA 7
fsp3 0.20
Lipinski(0=no;1=yes) 1

FDA
NDA 212839 (label) INN (CENOBAMATE) XCOPRI (SK LIFE) APPROVAL= AP YEAR= 2020
NDA 219403 (pdf not found) INN (CENOBAMATE) CENOBAMATE (ZENARA PHARMA PRIVATE LTD) APPROVAL= TA YEAR= 2025