e-Drug3D

1973

RELEBACTAM

INN
RELEBACTAM

cas 1174018-99-5

CLASS

ANTIINFECTIVES
A BETA-LACTAMASE INHIBITOR
ANTIBACTERIAL

ROUTE (list)

INTRAVENOUS

ATC code

J01DH56

PK parameters

VD 19 LITER
Cl 8 LITER / HOUR
PPB 22 PERCENT
t1/2 1.2 HOUR

Solubility

SOLUBLE IN WATER

Target

TARGET BETA-LACTAMASE

Beta-lactamase UNIPROT Q2PUH3 blaCTX-M-15

Beta-lactamase UNIPROT Q9X5A7 L2camp

Download SDF file

Sulfuric acid, mono[(1R,2S,5R)-7-oxo-2-[(4-piperidinylamino)carbonyl]-1,6-diazabicyclo[3.2.1]oct-6-yl] ester

Formula:
C12H20N4O6S

Calculated chemical properties:

MW 348.39
NB_atoms 23
XLogP -1.14
PSA 129.582
NB_HD 3
NB_HA 10
fsp3 0.83
Lipinski(0=no;1=yes) 1

FDA
NDA 212819 (label) INN (CILASTATIN SODIUM ; IMIPENEM ; RELEBACTAM) RECARBRIO (MSD MERCK CO) APPROVAL= AP YEAR= 2019