e-Drug3D

1963

REMIMAZOLAM

INN
REMIMAZOLAM

cas 308242-62-8

CLASS

NERVOUS SYSTEM
BENZODIAZEPINE
INDUCTION AND MAINTENANCE OF PROCEDURAL SEDATION
DID NOT SHOW CLEAR SELECTIVITY BETWEEN SUBTYPES OF THE GABAA RECEPTOR

ROUTE (list)

INTRAVENOUS

ATC code

N05CD14

PK parameters

VD 56.5 LITER (65 KILOGRAM)
Cl 64.5 LITER / HOUR
PPB 91 PERCENT
t1/2 0.75 HOUR

Solubility

SPARINGLY SOLUBLE IN WATER

Target

TARGET GAMMA AMINO BUTYRIC ACID TYPE A [GABAA] RECEPTOR

GABA-A receptor

Download SDF file

4H-Imidazo[1,2-a][1,4]benzodiazepine-4-propanoic acid, 8-bromo-1-methyl-6-(2-pyridinyl)-, methyl ester, (4S)-

Formula:
C21H19BrN4O2

Calculated chemical properties:

MW 439.30
NB_atoms 28
XLogP 4.18
PSA 55.756
NB_HD 0
NB_HA 6
fsp3 0.24
Lipinski(0=no;1=yes) 1

FDA
NDA 212295 (label) INN (REMIMAZOLAM BESYLATE) BYFAVO (ACACIA) APPROVAL= AP YEAR= 2020