e-Drug3D

1956

M DAROLUTAMIDE

INN
DAROLUTAMIDE

cas 1297537-33-7

CLASS

ANTINEOPLASTIC
ANDROGEN RECEPTOR INHIBITOR
TREATMENT OF NON-METASTATIC CASTRATION-RESISTANT PROSTATE CANCER

ROUTE (list)

ATC code

L02BB06

PK parameters

PPB 99.8 PERCENT
t1/2 20 HOUR

Target

TARGET ANDROGEN RECEPTOR (AR)

Androgen receptor UNIPROT P10275 AR

Download SDF file

1H-Pyrazole-3-carboxamide, 5-acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-

Formula:
C19H17ClN6O2

Calculated chemical properties:

MW 396.84
NB_atoms 28
XLogP 2.82
PSA 105.608
NB_HD 2
NB_HA 8
fsp3 0.21
Lipinski(0=no;1=yes) 1

FDA
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