e-Drug3D

1940

BREMELANOTIDE

INN
BREMELANOTIDE

cas 189691-06-3

CLASS

MELANOCORTIN RECEPTOR (MCR) AGONIST
TREATMENT OF PREMENOPAUSAL WOMEN WITH ACQUIRED, GENERALIZED HYPOACTIVE SEXUAL DESIRE DISORDER (HSDD)

ROUTE (list)

SUBCUTANEOUS

ATC code

G02CX05

PK parameters

F 100 PERCENT
Tmax 1 HOUR
VD 25 LITER
Cl 6.5 LITER / HOUR
PPB 21 PERCENT
t1/2 2.7 HOUR

Target

TARGET MELANOCORTIN RECEPTOR (MCR) MC1R, MC4R, MC3R, MC5R, MC2R

Melanocortin receptor 4 UNIPROT P32245 MC4R

Download SDF file

L-Lysine, N-acetyl-L-norleucyl-L-alpha-aspartyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-, (2->7)-lactam

Formula:
C50H68N14O10

Calculated chemical properties:

MW 1025.18
NB_atoms 74
XLogP -3.59
PSA 321.276
NB_HD 15
NB_HA 23
fsp3 0.46
Lipinski(0=no;1=yes) 0

FDA
NDA 210557 (pdf not found) INN (BREMELANOTIDE ACETATE) VYLEESI AUTOINJECTOR (COSETTE) APPROVAL= AP YEAR= 2019