e-Drug3D

1923

SOLRIAMFETOL

INN
SOLRIAMFETOL

cas 178429-62-4

CLASS

NERVOUS SYSTEM
A DOPAMINE AND NOREPINEPHRINE REUPTAKE INHIBITOR (DNRI)
TREATMENT OF EXCESSIVE DAYTIME SLEEPINESS ASSOCIATED WITH NARCOLEPSY OR OBSTRUCTIVE SLEEP APNEA (OSA)

ROUTE (list)

ORAL

ATC code

N06BA14

PK parameters

F 95 PERCENT
Tmax 2 HOUR
VD 199 LITER
Cl 19.5 LITER / HOUR
PPB 16.3 PERCENT
t1/2 7.1 HOUR

Solubility

FREELY SOLUBLE IN WATER

Target

TARGET DOPAMINE TRANSPORTER
NOREPINEPHRINE TRANSPORTER

DrugCentral

Unknown

Download SDF file

Benzenepropanol, beta-amino-, 1-carbamate, (betaR)-

Formula:
C10H14N2O2

Calculated chemical properties:

MW 194.23
NB_atoms 14
XLogP 0.65
PSA 74.522
NB_HD 4
NB_HA 4
fsp3 0.30
Lipinski(0=no;1=yes) 1

FDA
NDA 211230 (label) INN (SOLRIAMFETOL HYDROCHLORIDE) SUNOSI (AXSOME MALTA) APPROVAL= AP YEAR= 2019
NDA 218654 (pdf not found) INN (SOLRIAMFETOL) SOLRIAMFETOL (HETERO LABS LIMITED) APPROVAL= TA YEAR= 2024