e-Drug3D

1920

ERAVACYCLINE

INN
ERAVACYCLINE

cas 1207283-85-9

CLASS

ANTIINFECTIVES
TETRACYCLINE CLASS ANTIBACTERIAL
TREATMENT OF INTRA-ABDOMINAL INFECTIONS

ROUTE (list)

INTRAVENOUS

ATC code

J01AA13

PK parameters

VD 321 LITER
PPB 90 PERCENT
t1/2 20 HOUR

Target

TARGET 30S RIBOSOMAL SUBUNIT

DrugCentral

Unknown

Download SDF file

1-Pyrrolidineacetamide, N-[(5aR,6aS,7S,10aS)-9-(aminocarbonyl)-7-(dimethylamino)-4-fluoro-5,5a,6,6a,7,10,10a,12-octahydro-1,8,10a,11-tetrahydroxy-10,12-dioxo-2-naphthacenyl]-

Formula:
C27H31FN4O8

Calculated chemical properties:

MW 558.56
NB_atoms 40
XLogP 0.29
PSA 182.498
NB_HD 7
NB_HA 12
fsp3 0.48
Lipinski(0=no;1=yes) 0

FDA
NDA 211109 (pdf not found) INN (ERAVACYCLINE DIHYDROCHLORIDE) XERAVA (TETRAPHASE PHARMS) APPROVAL= AP YEAR= 2018 NEWMOLECULARENTITY