e-Drug3D

192

cas 58-38-8

CLASS

NERVOUS SYSTEM
ANTIPSYCHOTIC
ANTIEMETIC
DOPAMINE ANTAGONISTS
PHENOTHIAZINES

ROUTE (list)

ORAL INJECTION RECTAL

PK parameters

VD 1430 LITER (65 KILOGRAM)
Cl 62.4 LITER / HOUR (65 KILOGRAM)
t1/2 9 HOUR

TARGET D(2) DOPAMINE RECEPTOR

PDB
3M0W (STRUCTURE OF S100A4 WITH PCP)

Ligand code = P77 (link to the list of PDB complexes)

Download experimental 3D coordinates of P77 with added hydrogens

MW 373.94
NB_atoms 25
XLogP 4.58
PSA 14.344
NB_HD 0
NB_HA 3
fsp3 0.40
Lipinski(0=no;1=yes) 1

FDA
NDA 085178 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085579 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085580 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088597 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (MORTON GROVE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088598 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (MORTON GROVE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089251 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (SMITH AND NEPHEW) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089484 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (DURAMED PHARMS BARR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089485 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (DURAMED PHARMS BARR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089486 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (DURAMED PHARMS BARR) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089606 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089637 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089638 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 010571 (pdf not found) INN (PROCHLORPERAZINE MALEATE) COMPAZINE (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1956 NEWMOLECULARENTITY DISCONTINUED
NDA 010742 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) COMPAZINE (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1957 DISCONTINUED
NDA 011000 (pdf not found) INN (PROCHLORPERAZINE MALEATE) COMPAZINE (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1957 DISCONTINUED
NDA 011188 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) COMPAZINE (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1957 DISCONTINUED
NDA 011127 (pdf not found) INN (PROCHLORPERAZINE) COMPAZINE (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1959 DISCONTINUED
NDA 011276 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) COMPAZINE (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086348 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (WYETH AYERST) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 087153 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE (ALPHARMA US PHARMS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087154 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (ALPHARMA US PHARMS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087759 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 089530 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (WATSON LABS) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 089523 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (HIKMA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089605 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (WATSON LABS) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089675 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (MARSAM PHARMS LLC) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089703 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (HOSPIRA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089903 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (HIKMA) APPROVAL= AP YEAR= 1989
NDA 040058 (pdf not found) INN (PROCHLORPERAZINE) PROCHLORPERAZINE (COSETTE) APPROVAL= AP YEAR= 1993
NDA 040101 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (CHARTWELL RX) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 040120 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (TEVA PHARMS) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 040185 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (PHARMOBEDIENT) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 040207 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (DURAMED PHARMS BARR) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040162 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 040268 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCOMP (JUBILANT CADISTA) APPROVAL= AP YEAR= 1998
NDA 021019 (pdf not found) INN (PROCHLORPERAZINE MALEATE) COMPAZINE (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 040246 (pdf not found) INN (PROCHLORPERAZINE) COMPRO (PADAGIS US) APPROVAL= AP YEAR= 2000
NDA 040407 (pdf not found) INN (PROCHLORPERAZINE) PROCHLORPERAZINE (ABLE) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 040505 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (TEVA PARENTERAL) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 040540 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (SAGENT) APPROVAL= AP YEAR= 2004
NDA 204147 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (AVET LIFESCIENCES) APPROVAL= AP YEAR= 2013
NDA 210710 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2018
NDA 204860 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (NEXUS) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 214379 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (CAPLIN) APPROVAL= AP YEAR= 2021
NDA 213626 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (VIWIT PHARM) APPROVAL= AP YEAR= 2021
NDA 214107 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (GLAND) APPROVAL= AP YEAR= 2021
NDA 216202 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2022
NDA 213630 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (HIKMA) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 213873 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (EUGIA PHARMA) APPROVAL= AP YEAR= 2022
NDA 214192 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (AMNEAL) APPROVAL= AP YEAR= 2022
NDA 216495 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2022
NDA 216595 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2023
NDA 216598 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (AMNEAL) APPROVAL= AP YEAR= 2023
NDA 217478 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (BIONPHARMA) APPROVAL= AP YEAR= 2023
NDA 218515 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (AJANTA PHARMA LTD) APPROVAL= AP YEAR= 2024
NDA 212257 (pdf not found) INN (PROCHLORPERAZINE EDISYLATE) PROCHLORPERAZINE EDISYLATE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024
NDA 218912 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (LEADING) APPROVAL= AP YEAR= 2024
NDA 217847 (pdf not found) INN (PROCHLORPERAZINE MALEATE) PROCHLORPERAZINE MALEATE (CEROVENE INC) APPROVAL= AP YEAR= 2025