e-Drug3D

191

HYDROCORTAMATE

DISCONTINUED

INN
HYDROCORTAMATE

cas 76-47-1

CLASS

DERMATOLOGICALS
GLUCOCORTICOID
ANTI-INFLAMMATORY
CORTICOSTEROID
IMMUNOSUPPRESSIVE AGENTS

ROUTE (list)

TOPICAL

PK parameters

Target

TARGET GLUCOCORTICOID RECEPTOR

Glucocorticoid receptor UNIPROT P04150 NR3C1

Download SDF file

[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] 2-diethylaminoacetate

Formula:
C27H41NO6

Calculated chemical properties:

MW 475.61
NB_atoms 34
XLogP 2.67
PSA 93.59
NB_HD 2
NB_HA 7
fsp3 0.81
Lipinski(0=no;1=yes) 1

FDA
NDA 010554 (pdf not found) INN (HYDROCORTAMATE HYDROCHLORIDE) MAGNACORT (PFIZER) APPROVAL= AP YEAR= 1956 NEWMOLECULARENTITY DISCONTINUED