e-Drug3D

1900

GLYCOPYRRONIUM

INN
GLYCOPYRRONIUM

cas 596-51-0

CLASS

METABOLISM
ANTICHOLINERGIC
COMPETITIVE INHIBITOR OF ACETYLCHOLINE RECEPTORS
TREATMENT OF PRIMARY AXILLARY HYPERHIDROSIS

ROUTE (list)

TOPICAL

PK parameters

Tmax 1 HOUR
VD 27.3 LITER (65 KILOGRAM)

Target

TARGET MUSCARINIC ACETYLCHOLINE RECEPTOR

Muscarinic acetylcholine receptor M1 UNIPROT P11229 CHRM1

Muscarinic acetylcholine receptor M2 UNIPROT P08172 CHRM2

Download SDF file

Pyrrolidinium, 3-[(2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethyl-

Formula:
C19H28NO3

Calculated chemical properties:

MW 318.42
NB_atoms 23
XLogP 2.46
PSA 39.146
NB_HD 1
NB_HA 3
fsp3 0.63
Lipinski(0=no;1=yes) 1

FDA
NDA 210361 (label) INN (GLYCOPYRRONIUM TOSYLATE) QBREXZA (JOURNEY) APPROVAL= AP YEAR= 2018