e-Drug3D

1897

cas 179474-81-8

CLASS

METABOLISM
SEROTONIN-4 (5-HT4) RECEPTOR AGONIST
TREATMENT OF CHRONIC IDIOPATHIC CONSTIPATION (CIC)

ROUTE (list)

ORAL

PK parameters

F 90 PERCENT
Tmax 2.5 HOUR
VD 567 LITER
Cl 19 LITER / HOUR
PPB 30 PERCENT
t1/2 24 HOUR

MW 367.87
NB_atoms 25
XLogP 2.09
PSA 76.138
NB_HD 3
NB_HA 6
fsp3 0.61
Lipinski(0=no;1=yes) 1

FDA
NDA 210166 (label) INN (PRUCALOPRIDE SUCCINATE) MOTEGRITY (TAKEDA PHARMS USA) APPROVAL= AP YEAR= 2018 NEWMOLECULARENTITY
NDA 218492 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (NOVITIUM PHARMA) APPROVAL= AP YEAR= 2024
NDA 217662 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (HIKMA) APPROVAL= AP YEAR= 2025
NDA 218056 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2025
NDA 218177 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (MSN) APPROVAL= AP YEAR= 2025
NDA 218295 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (ALKEM LABS LTD) APPROVAL= AP YEAR= 2025
NDA 218778 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (TORRENT) APPROVAL= AP YEAR= 2025 DISCONTINUED
NDA 218795 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (ZENARA) APPROVAL= AP YEAR= 2025
NDA 218812 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (SKG PHARMA) APPROVAL= AP YEAR= 2025
NDA 218847 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (LUPIN LTD) APPROVAL= AP YEAR= 2025
NDA 218963 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (APPCO) APPROVAL= AP YEAR= 2025
NDA 218977 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (APOTEX) APPROVAL= AP YEAR= 2025
NDA 219071 (pdf not found) INN (PRUCALOPRIDE) PRUCALOPRIDE (TEVA PHARMS INC) APPROVAL= TA YEAR= 2025
NDA 219078 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (SOMERSET THERAP) APPROVAL= AP YEAR= 2025
NDA 219160 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (ANNORA PHARMA) APPROVAL= AP YEAR= 2025
NDA 219193 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (SPECGX LLC) APPROVAL= AP YEAR= 2025
NDA 219216 (pdf not found) INN (PRUCALOPRIDE SUCCINATE) PRUCALOPRIDE SUCCINATE (H2-PHARMA) APPROVAL= AP YEAR= 2025