e-Drug3D

1895

OMADACYCLINE

INN
OMADACYCLINE

cas 389139-89-3

CLASS

ANTIINFECTIVES
TETRACYCLINE CLASS OF ANTIBACTERIAL DRUGS

ROUTE (list)

ORAL INTRAVENOUS

ATC code

J01AA15

PK parameters

F 34.5 PERCENT
Tmax 2.75 HOUR
VD 190 LITER
Cl 34.6 LITER / HOUR
PPB 20 PERCENT
t1/2 16.8 HOUR

Target

TARGET 30S RIBOSOMAL SUBUNIT

DrugCentral

Unknown

Download SDF file

2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-9-[[(2,2-dimethylpropyl)amino]methyl]-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)-

Formula:
C29H40N4O7

Calculated chemical properties:

MW 556.65
NB_atoms 40
XLogP 1.32
PSA 168.184
NB_HD 7
NB_HA 11
fsp3 0.55
Lipinski(0=no;1=yes) 0

FDA
NDA 209816 (label) INN (OMADACYCLINE TOSYLATE) NUZYRA (PARATEK PHARMS INC) APPROVAL= AP YEAR= 2018 NEWMOLECULARENTITY
NDA 209817 (label) INN (OMADACYCLINE TOSYLATE) NUZYRA (PARATEK PHARMS INC) APPROVAL= AP YEAR= 2018