e-Drug3D

1884

M APALUTAMIDE

INN
APALUTAMIDE

cas 1332391-11-3

CLASS

ANTINEOPLASTIC
ANDROGEN RECEPTOR INHIBITOR INDICATED FOR THE TREATMENT OF PATIENTS WITH NON-METASTATIC CASTRATION-RESISTANT PROSTATE CANCER
N-DESMETHYL APALUTAMIDE, IS A LESS POTENT INHIBITOR OF AR, AND EXHIBITED ONE-THIRD THE ACTIVITY

ROUTE (list)

ATC code

L02BB05

PK parameters

PPB 95 PERCENT

Target

TARGET ANDROGEN RECEPTOR

DrugCentral

Androgen receptor UNIPROT P10275 AR

Download SDF file

Benzamide, 4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-

Formula:
C20H13F4N5O2S

Calculated chemical properties:

MW 463.42
NB_atoms 32
XLogP 3.27
PSA 90.889
NB_HD 2
NB_HA 7
fsp3 0.25
Lipinski(0=no;1=yes) 1

FDA
-