e-Drug3D

1872

BENZNIDAZOLE

INN
BENZNIDAZOLE

cas 22994-85-0

CLASS

ANTIPARASITIC
A NITROIMIDAZOLE ANTIMICROBIAL
TREATMENT OF CHAGAS DISEASE CAUSED BY TRYPANOSOMA CRUZI
BENZNIDAZOLE INHIBITS THE SYNTHESIS OF DNA, RNA, AND PROTEINS WITHIN THE T. CRUZI PARASITE

ROUTE (list)

ORAL

ATC code

P01CA02

PK parameters

Tmax 2 HOUR
PPB 52 PERCENT
t1/2 13 HOUR

Solubility

PRACTICALLY INSOLUBLE IN WATER

Target

TARGET DNA

DrugCentral

Unknown

Download SDF file

1H-Imidazole-1-acetamide, 2-nitro-N-(phenylmethyl)-

Formula:
C12H12N4O3

Calculated chemical properties:

MW 260.26
NB_atoms 19
XLogP 1.11
PSA 81.788
NB_HD 1
NB_HA 6
fsp3 0.17
Lipinski(0=no;1=yes) 1

FDA
NDA 209570 (pdf not found) INN (BENZNIDAZOLE) BENZNIDAZOLE (CHEMO RESEARCH SL) APPROVAL= AP YEAR= 2017