e-Drug3D

1869

ANGIOTENSIN II

INN
ANGIOTENSIN II

cas 4474-91-3

CLASS

CARDIOVASCULAR
A VASOCONSTRICTOR TO INCREASE BLOOD PRESSURE IN ADULTS WITH SEPTIC OR OTHER DISTRIBUTIVE SHOCK

ROUTE (list)

INTRAVENOUS

ATC code

C01CX09

PK parameters

t1/2 0.016 HOUR

Solubility

SOLUBLE IN WATER

Target

TARGET G-PROTEIN-COUPLED ANGIOTENSIN II RECEPTOR TYPE 1

DrugCentral

Type-1 angiotensin II receptor UNIPROT P30556 AGTR1

Download SDF file

Angiotensin II, 5-L-isoleucine-

Formula:
C50H71N13O12

Calculated chemical properties:

MW 1045.19
NB_atoms 75
XLogP -5.59
PSA 366.019
NB_HD 15
NB_HA 24
fsp3 0.50
Lipinski(0=no;1=yes) 0

FDA
NDA 209360 (label) INN (ANGIOTENSIN II ACETATE) GIAPREZA (LA JOLLA PHARMA) APPROVAL= AP YEAR= 2017 NEWMOLECULARENTITY
NDA 216966 (pdf not found) INN (ANGIOTENSIN II ACETATE) ANGIOTENSIN LL ACETATE (GLAND) APPROVAL= AP YEAR= 2025