e-Drug3D

1858

LATANOPROSTENE BUNOD

INN
LATANOPROSTENE BUNOD

cas 860005-21-6

CLASS

SENSORY
ANTIGLAUCOMA
ANTIHYPERTENSIVE AGENTS
PROSTAGLANDIN ANALOG
LOWER INTRAOCULAR PRESSURE BY INCREASING OUTFLOW OF AQUEOUS HUMOR

ROUTE (list)

OPHTHALMIC

ATC code

S01EE06

PK parameters

Target

DrugCentral

Prostaglandin F2-alpha receptor UNIPROT P43088 PTGFR

Download SDF file

5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-, 4-(nitrooxy)butyl ester, (5Z)-

Formula:
C27H41NO8

Calculated chemical properties:

MW 507.61
NB_atoms 36
XLogP 3.77
PSA 141.356
NB_HD 3
NB_HA 8
fsp3 0.67
Lipinski(0=no;1=yes) 0

FDA
NDA 207795 (pdf not found) INN (LATANOPROSTENE BUNOD) VYZULTA (BAUSCH AND LOMB) APPROVAL= AP YEAR= 2017 NEWMOLECULARENTITY
NDA 217387 (pdf not found) INN (LATANOPROSTENE BUNOD) LATANOPROSTENE BUNOD (GLAND) APPROVAL= AP YEAR= 2025