e-Drug3D

1857

MACIMORELIN

DISCONTINUED

INN
MACIMORELIN

cas 381231-18-1

CLASS

VARIOUS
TESTS FOR PITUITARY FUNCTION
GROWTH HORMONE (GH) SECRETAGOGUE RECEPTOR AGONIST INDICATED FOR THE DIAGNOSIS OF ADULT GROWTH HORMONE DEFICIENCY

ROUTE (list)

ORAL

ATC code

V04CD06

PK parameters

Tmax 1 HOUR
t1/2 4.1 HOUR

Target

TARGET GROWTH HORMONE SECRETAGOGUE RECEPTOR (GHS-R)

Growth hormone secretagogue receptor type 1 UNIPROT Q92847 GHSR

Download SDF file

D-Tryptophanamide, 2-methylalanyl-N-[(1R)-1-(formylamino)-2-(1H-indol-3-yl)ethyl]-

Formula:
C26H30N6O3

Calculated chemical properties:

MW 474.56
NB_atoms 35
XLogP 1.84
PSA 127.838
NB_HD 7
NB_HA 9
fsp3 0.27
Lipinski(0=no;1=yes) 0

FDA
NDA 205598 (pdf not found) INN (MACIMORELIN ACETATE) MACRILEN (NOVO) APPROVAL= AP YEAR= 2017 NEWMOLECULARENTITY DISCONTINUED