e-Drug3D

185

cas 6893-02-3

CLASS

HORMONES
THYROMIMETIC
THYROID HORMONE

ROUTE (list)

ORAL INJECTION

PK parameters

F 95 PERCENT
t1/2 60 HOUR

TARGET THYROID HORMONE RECEPTOR

PDB
4LNW (CRYSTAL STRUCTURE OF TR-ALPHA BOUND TO T3 IN A SECOND SITE)

Ligand code = T3 (link to the list of PDB complexes)

Download experimental 3D coordinates of T3 with added hydrogens

MW 649.95
NB_atoms 23
XLogP 2.62
PSA 90.193
NB_HD 3
NB_HA 5
fsp3 0.13
Lipinski(0=no;1=yes) 0

FDA
NDA 010379 (label) INN (LIOTHYRONINE SODIUM) CYTOMEL (KING PHARMS) APPROVAL= AP YEAR= 1956
NDA 085753 (pdf not found) INN (LIOTHYRONINE SODIUM) LIOTHYRONINE SODIUM (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 085755 (pdf not found) INN (LIOTHYRONINE SODIUM) LIOTHYRONINE SODIUM (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 020105 (label) INN (LIOTHYRONINE SODIUM) TRIOSTAT (PH HEALTH) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 076923 (pdf not found) INN (LIOTHYRONINE SODIUM) LIOTHYRONINE SODIUM (XGEN PHARMS) APPROVAL= AP YEAR= 2005
NDA 090097 (pdf not found) INN (LIOTHYRONINE SODIUM) LIOTHYRONINE SODIUM (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2009
NDA 090326 (pdf not found) INN (LIOTHYRONINE SODIUM) LIOTHYRONINE SODIUM (PHARMOBEDIENT) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 200295 (pdf not found) INN (LIOTHYRONINE SODIUM) LIOTHYRONINE SODIUM (SIGMAPHARM LABS LLC) APPROVAL= AP YEAR= 2012
NDA 091382 (pdf not found) INN (LIOTHYRONINE SODIUM) LIOTHYRONINE SODIUM (SUN PHARM) APPROVAL= AP YEAR= 2016
NDA 211510 (pdf not found) INN (LIOTHYRONINE SODIUM) LIOTHYRONINE SODIUM (TEVA PHARMS USA) APPROVAL= AP YEAR= 2018
NDA 214803 (pdf not found) INN (LIOTHYRONINE SODIUM) LIOTHYRONINE SODIUM (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2021
NDA 218070 (pdf not found) INN (LIOTHYRONINE SODIUM) LIOTHYRONINE SODIUM (BIOCON PHARMA) APPROVAL= AP YEAR= 2024