e-Drug3D

1849

M VALBENAZINE

INN
VALBENAZINE

cas 3466-75-9

CLASS

NERVOUS SYSTEM
VESICULAR MONOAMINE TRANSPORTER 2 (VMAT2) INHIBITOR (KI = 3 NANOMOLAR)
TREATMENT OF ADULTS WITH TARDIVE DYSKINESIA

ROUTE (list)

ATC code

N07XX13

PK parameters

Tmax 6 HOUR
PPB 64 PERCENT
t1/2 22 HOUR

Target

TARGET VESICULAR MONOAMINE TRANSPORTER 2 (VMAT2)

Synaptic vesicular amine transporter UNIPROT Q05940 SLC18A2

Download SDF file

2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-

Formula:
C19H29NO3

Calculated chemical properties:

MW 319.43
NB_atoms 23
XLogP 3.03
PSA 47.698
NB_HD 1
NB_HA 4
fsp3 0.68
Lipinski(0=no;1=yes) 1

FDA
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