e-Drug3D

1846

cas 89-25-8

CLASS

NERVOUS SYSTEM
TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)

ROUTE (list)

INTRAVENOUS ORAL INJECTION

PK parameters

PPB 92 PERCENT
t1/2 5.25 HOUR

-

PDB
5S52 (TUBULIN-Z50145861-COMPLEX)

Ligand code = W1P (link to the list of PDB complexes)

Download experimental 3D coordinates of W1P with added hydrogens

MW 174.20
NB_atoms 13
XLogP 1.80
PSA 29.837
NB_HD 0
NB_HA 3
fsp3 0.20
Lipinski(0=no;1=yes) 1

FDA
NDA 209176 (label) INN (EDARAVONE) RADICAVA (MITSUBISHI TANABE) APPROVAL= AP YEAR= 2017 NEWMOLECULARENTITY
NDA 215446 (label) INN (EDARAVONE) RADICAVA ORS (KK BCJ-94) APPROVAL= AP YEAR= 2022
NDA 215508 (pdf not found) INN (EDARAVONE) EDARAVONE (HIKMA) APPROVAL= AP YEAR= 2024
NDA 215917 (pdf not found) INN (EDARAVONE) EDARAVONE (DR REDDYS) APPROVAL= AP YEAR= 2024
NDA 216199 (pdf not found) INN (EDARAVONE) EDARAVONE (GLAND) APPROVAL= AP YEAR= 2024
NDA 218349 (pdf not found) INN (EDARAVONE) EDARAVONE (ZYDUS PHARMS USA INC) APPROVAL= TA YEAR= 2024
NDA 218354 (pdf not found) INN (EDARAVONE) EDARAVONE (LONG GROVE PHARMS) APPROVAL= AP YEAR= 2024
NDA 216902 (pdf not found) INN (EDARAVONE) EDARAVONE (SANDOZ) APPROVAL= AP YEAR= 2024
NDA 217565 (pdf not found) INN (EDARAVONE) EDARAVONE (XGEN PHARMS) APPROVAL= AP YEAR= 2024