e-Drug3D

1833

ETELCALCETIDE

INN
ETELCALCETIDE

cas 1262780-97-1

CLASS

HORMONES
TREATMENT OF SECONDARY HYPERPARATHYROIDISM (HPT) WITH CHRONIC KIDNEY DISEASE (CKD) ON HEMODIALYSIS
CALCIUM-SENSING RECEPTOR (CASR) AGONIST

ROUTE (list)

INTRAVENOUS

ATC code

H05BX04

PK parameters

VD 796 LITER
Cl 7.66 LITER / HOUR
PPB 47 PERCENT
t1/2 84 HOUR

Solubility

SOLUBLE IN WATER

Target

TARGET CALCIUM-SENSING RECEPTOR (CASR)

Extracellular calcium-sensing receptor UNIPROT P41180 CASR

Download SDF file

D-Argininamide, N-acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-, disulfide with L-cysteine

Formula:
C38H73N21O10S2

Calculated chemical properties:

MW 1051.34
NB_atoms 71
XLogP -15.84
PSA 520.841
NB_HD 31
NB_HA 27
fsp3 0.66
Lipinski(0=no;1=yes) 0

FDA
NDA 208325 (label) INN (ETELCALCETIDE) PARSABIV (KAI PHARMS INC) APPROVAL= AP YEAR= 2017 NEWMOLECULARENTITY