e-Drug3D

1832

BETRIXABAN

DISCONTINUED

INN
BETRIXABAN

cas 330942-05-7

CLASS

BLOOD
PROPHYLAXIS OF VENOUS THROMBOEMBOLISM (VTE)
FACTOR XA (FXA) INHIBITOR

ROUTE (list)

ORAL

ATC code

B01AF04

PK parameters

F 34 PERCENT
Tmax 3.5 HOUR
VD 2080 LITER (65 KILOGRAM)
PPB 60 PERCENT
t1/2 23 HOUR

Target

TARGET FACTOR XA (FXA)

Coagulation factor X UNIPROT P00742 F10

Download SDF file

Benzamide, N-(5-chloro-2-pyridinyl)-2-[[4-[(dimethylamino)iminomethyl]benzoyl]amino]-5-methoxy-

Formula:
C23H22ClN5O3

Calculated chemical properties:

MW 451.91
NB_atoms 32
XLogP 4.14
PSA 89.306
NB_HD 3
NB_HA 8
fsp3 0.13
Lipinski(0=no;1=yes) 1

FDA
NDA 208383 (label) INN (BETRIXABAN) BEVYXXA (PORTOLA PHARMS INC) APPROVAL= AP YEAR= 2017 NEWMOLECULARENTITY DISCONTINUED