e-Drug3D

1804

ARIPIPRAZOLE LAUROXIL

INN
ARIPIPRAZOLE LAUROXIL

(has an active metabolite)

cas 1259305-29-7

CLASS

NERVOUS SYSTEM
ANTIPSYCHOTICS
TREATMENT OF BIPOLAR I DISORDER (SCHIZOPHRENIA)
PRODRUG OF ARIPIPRAZOLE

ROUTE (list)

INTRAMUSCULAR

ATC code

N05AX12

PK parameters

Target

TARGET 5-HYDROXYTRYPTAMINE 1A RECEPTOR
5-HYDROXYTRYPTAMINE 2A RECEPTOR
D2 DOPAMINE RECEPTOR
ADRENERGIC ALPHA1 RECEPTOR

DrugCentral

D(2) dopamine receptor UNIPROT P14416 DRD2

5-hydroxytryptamine receptor 2A UNIPROT P28223 HTR2A

Download SDF file

Dodecanoic acid, [7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2-oxo-1(2H)-quinolinyl]methyl ester

Formula:
C36H51Cl2N3O4

Calculated chemical properties:

MW 660.70
NB_atoms 45
XLogP 8.68
PSA 64.142
NB_HD 0
NB_HA 7
fsp3 0.61
Lipinski(0=no;1=yes) 0

FDA
NDA 207533 (label) INN (ARIPIPRAZOLE LAUROXIL) ARISTADA (ALKERMES INC) APPROVAL= AP YEAR= 2015 NEWMOLECULARENTITY
NDA 209830 (label) INN (ARIPIPRAZOLE LAUROXIL) ARISTADA INITIO KIT (ALKERMES INC) APPROVAL= AP YEAR= 2018