e-Drug3D

179

AMBENONIUM

DISCONTINUED

INN
AMBENONIUM

cas 7648-98-8

CLASS

NERVOUS SYSTEM
CHOLINESTERASE INHIBITOR
CHOLINERGIC
ANTIARRHYTHMIC AGENTS
TREATMENT OF MYASTHENIA GRAVIS

ROUTE (list)

ORAL

ATC code

N07AA30

PK parameters

VD 16.6 LITER (65 KILOGRAM)

Solubility

SOLUBLE IN WATER TO 20 PERCENT

Target

TARGET CHOLINESTERASE

Acetylcholinesterase UNIPROT P22303 ACHE

Download SDF file

(2-chlorophenyl)methyl-[2-[[2-[2-[(2-chlorophenyl)methyl-diethylazaniumyl]ethylamino]-2-oxoacetyl]amino]ethyl]-diethylazanium

Formula:
C28H42Cl2N4O2

Calculated chemical properties:

MW 537.56
NB_atoms 36
XLogP 4.64
PSA 58.902
NB_HD 2
NB_HA 4
fsp3 0.50
Lipinski(0=no;1=yes) 0

FDA
NDA 010155 (label) INN (AMBENONIUM CHLORIDE) MYTELASE (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1956 DISCONTINUED