e-Drug3D

178

cas 84-80-0

CLASS

VITAMIN
PROTHROMBOGENIC
ANTIFIBRINOLYTIC AGENTS

ROUTE (list)

ORAL INJECTION INTRAVENOUS

PK parameters

-

PDB
4XK8 (CRYSTAL STRUCTURE OF PLANT PHOTOSYSTEM I-LHCI SUPER-COMPLEX AT 2.8 ANGSTROM RESOLUTION)

Ligand code = PQN (link to the list of PDB complexes)

Download experimental 3D coordinates of PQN with added hydrogens

MW 450.68
NB_atoms 33
XLogP 9.16
PSA 33.044
NB_HD 0
NB_HA 2
fsp3 0.61
Lipinski(0=no;1=yes) 0

FDA
NDA 011745 (pdf not found) INN (PHYTONADIONE) KONAKION (ROCHE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 084060 (pdf not found) INN (PHYTONADIONE) PHYTONADIONE (GLAXOSMITHKLINE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 010104 (label) INN (PHYTONADIONE) MEPHYTON (BAUSCH) APPROVAL= AP YEAR= 1955 DISCONTINUED
NDA 012223 (label) INN (PHYTONADIONE) AQUAMEPHYTON (PAI HOLDINGS PHARM) APPROVAL= AP YEAR= 1960 DISCONTINUED
NDA 083722 (label) INN (PHYTONADIONE) PHYTONADIONE (INTL MEDICATION) APPROVAL= AP YEAR= 1976
NDA 018920 (label) INN (PHYTONADIONE) M.V.I. PEDIATRIC (HOSPIRA) APPROVAL= AP YEAR= 1983
NDA 087954 (pdf not found) INN (PHYTONADIONE) VITAMIN K1 (HOSPIRA) APPROVAL= AP YEAR= 1983
NDA 087955 (pdf not found) INN (PHYTONADIONE) VITAMIN K1 (HOSPIRA) APPROVAL= AP YEAR= 1983
NDA 087956 (pdf not found) INN (PHYTONADIONE) VITAMIN K1 (HOSPIRA) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 020176 (pdf not found) INN (PHYTONADIONE) VITAPED (HOSPIRA) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 021163 (label) INN (VITAMIN K) INFUVITE ADULT (SANDOZ) APPROVAL= AP YEAR= 2000
NDA 021265 (label) INN (TOCOPHEROL ACETATE) INFUVITE PEDIATRIC (SANDOZ) APPROVAL= AP YEAR= 2001
NDA 021559 (label) INN (VITAMIN K) INFUVITE ADULT (SANDOZ) APPROVAL= AP YEAR= 2003 OBSOLETE
NDA 021625 (label) INN (VITAMIN K) M.V.I. ADULT (HOSPIRA) APPROVAL= AP YEAR= 2004
NDA 021643 (label) INN (VITAMIN K) M.V.I. ADULT (PHARMACY BULK PACKAGE) (HOSPIRA) APPROVAL= AP YEAR= 2004
NDA 021646 (label) INN (TOCOPHEROL ACETATE) INFUVITE PEDIATRIC (PHARMACY BULK PACKAGE) (SANDOZ) APPROVAL= AP YEAR= 2004 OBSOLETE
NDA 209373 (pdf not found) INN (PHYTONADIONE) PHYTONADIONE (AMNEAL PHARMS CO) APPROVAL= AP YEAR= 2018
NDA 207719 (pdf not found) INN (PHYTONADIONE) PHYTONADIONE (DR REDDYS) APPROVAL= AP YEAR= 2019
NDA 210189 (pdf not found) INN (PHYTONADIONE) PHYTONADIONE (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2019
NDA 212424 (pdf not found) INN (PHYTONADIONE) PHYTONADIONE (CIPLA) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 214596 (pdf not found) INN (PHYTONADIONE) PHYTONADIONE (CIPLA) APPROVAL= AP YEAR= 2022
NDA 213329 (pdf not found) INN (PHYTONADIONE) PHYTONADIONE (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2023
NDA 213336 (pdf not found) INN (PHYTONADIONE) PHYTONADIONE (AGNITIO) APPROVAL= AP YEAR= 2023
NDA 212112 (pdf not found) INN (PHYTONADIONE) PHYTONADIONE (HIKMA) APPROVAL= AP YEAR= 2024 DISCONTINUED
NDA 217386 (pdf not found) INN (PHYTONADIONE) PHYTONADIONE (GLAND) APPROVAL= AP YEAR= 2024
NDA 214966 (pdf not found) INN (PHYTONADIONE) PHYTONADIONE (CIPLA) APPROVAL= AP YEAR= 2025
NDA 219212 (pdf not found) INN (PHYTONADIONE) PHYTONADIONE (CAPLIN) APPROVAL= AP YEAR= 2025