e-Drug3D

1778

CANGRELOR

INN
CANGRELOR

cas 163706-06-7

CLASS

BLOOD
P2Y12 PLATELET RECEPTOR INHIBITOR

ROUTE (list)

INTRAVENOUS

ATC code

B01AC25

PK parameters

Tmax 0.033 HOUR
VD 3.9 LITER
Cl 36 LITER / HOUR (EQN)
PPB 97.5 PERCENT
t1/2 0.075 HOUR

Target

TARGET P2Y12 PLATELET RECEPTOR

DrugCentral

P2Y purinoceptor 12 UNIPROT Q9H244 P2RY12

Download SDF file

5'-Adenylic acid, N-[2-(methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-, anhydride with P,P'-(dichloromethylene)bis[phosphonic acid] (1:1)

Formula:
C17H25Cl2F3N5O12P3S2

Calculated chemical properties:

MW 772.34
NB_atoms 44
XLogP 0.32
PSA 242.151
NB_HD 3
NB_HA 17
fsp3 0.71
Lipinski(0=no;1=yes) 0

FDA
NDA 204958 (pdf not found) INN (CANGRELOR) KENGREAL (CHIESI) APPROVAL= AP YEAR= 2015 NEWMOLECULARENTITY
NDA 213551 (pdf not found) INN (CANGRELOR) CANGRELOR (GLAND) APPROVAL= AP YEAR= 2025