e-Drug3D

1761

HALOTHANE

DISCONTINUED

INN
HALOTHANE

cas 151-67-7

CLASS

NERVOUS SYSTEM
ANESTHETIC

ROUTE (list)

INHALATION

ATC code

N01AB01

PK parameters

Target

TARGET POLYPHARMACOLOGY (VOLTAGE-DEPENDENT ANION CHANNEL, GABA, PMID24563623)

PDB
1XZ1 (COMPLEX OF HALOTHANE WITH APOFERRITIN)

Ligand code = HLT_1XZ1 (link to the list of PDB complexes)

Download experimental 3D coordinates of HLT_1XZ1 with added hydrogens

DrugCentral

Potassium channel subfamily K member 2 UNIPROT O95069 KCNK2

Potassium channel subfamily K member 3 UNIPROT O14649 KCNK3

Download SDF file

2-bromo-2-chloro-1,1,1-trifluoroethane

Formula:
C2HBrClF3

Calculated chemical properties:

MW 197.38
NB_atoms 7
XLogP 2.51
PSA 0
NB_HD 0
NB_HA 0
fsp3 1.00
Lipinski(0=no;1=yes) 1

FDA
NDA 011338 (pdf not found) INN (HALOTHANE) FLUOTHANE (WYETH AYERST) APPROVAL= AP YEAR= 1958 DISCONTINUED
NDA 080810 (pdf not found) INN (HALOTHANE) HALOTHANE (HALOCARBON) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 083254 (pdf not found) INN (HALOTHANE) HALOTHANE (HOSPIRA) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 084977 (pdf not found) INN (HALOTHANE) HALOTHANE (BH) APPROVAL= AP YEAR= 1976 DISCONTINUED