e-Drug3D

1754

M CLOFIBRATE

INN
CLOFIBRATE

cas 882-09-7

CLASS

CARDIOVASCULAR
HYPOLIPIDEMIC
ANTICHOLESTEREMIC AGENTS
ANTILIPIDEMIC AGENTS
REDUCE THE VERY LOW-DENSITY LIPOPROTEIN FRACTION

ROUTE (list)

ATC code

C10AB01

PK parameters

PPB 96 PERCENT
t1/2 20 HOUR

Target

TARGET PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR

PDB
7BPY (X-RAY STRUCTURE OF HUMAN PPARALPHA LIGAND BINDING DOMAIN-CLOFIBRIC ACID-SRC1 COACTIVATOR PEPTIDE CO-CRYSTALS OBTAINED BY DELIPIDATION AND CO-CRYSTALLIZATION)

Ligand code = E0O (link to the list of PDB complexes)

Download experimental 3D coordinates of E0O with added hydrogens

DrugCentral

Peroxisome proliferator-activated receptor alpha UNIPROT Q07869 PPARA

Download SDF file

Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-

Formula:
C10H11ClO3

Calculated chemical properties:

MW 213.63
NB_atoms 14
XLogP 1.25
PSA 45.716
NB_HD 0
NB_HA 3
fsp3 0.30
Lipinski(0=no;1=yes) 1

FDA
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