e-Drug3D

1724

FINAFLOXACIN

DISCONTINUED

INN
FINAFLOXACIN

cas 209342-40-5

CLASS

ANTIINFECTIVES
FLUOROQUINOLONE ANTIMICROBIAL INDICATED FOR THE TREATMENT OF ACUTE OTITIS EXTERNA
TYPE II TOPOISOMERASE INHIBITOR

ROUTE (list)

OTIC

ATC code

PK parameters

Solubility

SLIGHTLY SOLUBLE IN WATER (0.125 MILLIGRAM / MILLILITER)

Target

TARGET DNA GYRASE
TOPOISOMERASE IV

Unknown

Download SDF file

3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-

Formula:
C20H19FN4O4

Calculated chemical properties:

MW 397.38
NB_atoms 29
XLogP -0.11
PSA 100.543
NB_HD 1
NB_HA 8
fsp3 0.45
Lipinski(0=no;1=yes) 1

FDA
NDA 206307 (label) INN (FINAFLOXACIN) XTORO (FONSECA BIOSCIENCES) APPROVAL= AP YEAR= 2014 NEWMOLECULARENTITY DISCONTINUED