e-Drug3D

1722

cas 23651-95-8

CLASS

CARDIOVASCULAR
TREATMENT OF ORTHOSTATIC DIZZINESS AND LIGHTHEADEDNESS
SYNTHETIC AMINO ACID PRECURSOR OF NOREPINEPHRINE
SUBSTRATE OF DOPA-DECARBOXYLASE

ROUTE (list)

ORAL

PK parameters

Tmax 2 HOUR
VD 200 LITER
Cl 55.4 LITER / HOUR (EQN)
PPB 75 PERCENT
t1/2 2.5 HOUR

MW 212.18
NB_atoms 15
XLogP -1.79
PSA 117.983
NB_HD 5
NB_HA 6
fsp3 0.22
Lipinski(0=no;1=yes) 1

FDA
NDA 203202 (label) INN (DROXIDOPA) NORTHERA (LUNDBECK NA LTD) APPROVAL= AP YEAR= 2014
NDA 211818 (pdf not found) INN (DROXIDOPA) DROXIDOPA (ZYDUS PHARMS) APPROVAL= AP YEAR= 2021
NDA 211652 (pdf not found) INN (DROXIDOPA) DROXIDOPA (LUPIN PHARMS) APPROVAL= AP YEAR= 2021
NDA 211726 (pdf not found) INN (DROXIDOPA) DROXIDOPA (ANNORA) APPROVAL= AP YEAR= 2021
NDA 211741 (pdf not found) INN (DROXIDOPA) DROXIDOPA (MSN PHARMS INC) APPROVAL= AP YEAR= 2021
NDA 212835 (pdf not found) INN (DROXIDOPA) DROXIDOPA (HIKMA) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 213033 (pdf not found) INN (DROXIDOPA) DROXIDOPA (BIONPHARMA) APPROVAL= AP YEAR= 2021
NDA 213162 (pdf not found) INN (DROXIDOPA) DROXIDOPA (TEVA PHARMS USA INC) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 213661 (pdf not found) INN (DROXIDOPA) DROXIDOPA (UPSHER SMITH LABS) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 213911 (pdf not found) INN (DROXIDOPA) DROXIDOPA (ALKEM LABS LTD) APPROVAL= AP YEAR= 2021
NDA 214017 (pdf not found) INN (DROXIDOPA) DROXIDOPA (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2021
NDA 214384 (pdf not found) INN (DROXIDOPA) DROXIDOPA (SUN PHARM) APPROVAL= AP YEAR= 2021
NDA 214387 (pdf not found) INN (DROXIDOPA) DROXIDOPA (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2021
NDA 214391 (pdf not found) INN (DROXIDOPA) DROXIDOPA (JUBILANT CADISTA) APPROVAL= AP YEAR= 2021
NDA 214543 (pdf not found) INN (DROXIDOPA) DROXIDOPA (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2021
NDA 215265 (pdf not found) INN (DROXIDOPA) DROXIDOPA (ADAPTIS) APPROVAL= AP YEAR= 2021
NDA 214217 (pdf not found) INN (DROXIDOPA) DROXIDOPA (CHARTWELL RX) APPROVAL= AP YEAR= 2022 DISCONTINUED