e-Drug3D

1712

cas 164650-44-6

CLASS

ANTIINFECTIVES
AZOLE ANTIFUNGAL INDICATED FOR THE TOPICAL TREATMENT OF ONYCHOMYCOSIS OF THE TOENAILS DUE TO TRICHOPHYTON RUBRUM AND TRICHOPHYTON MENTAGROPHYTES
INHIBITS FUNGAL LANOSTEROL 14 ALPHA-DEMETHYLASE

ROUTE (list)

TOPICAL

PK parameters

t1/2 29.9 HOUR

MW 348.40
NB_atoms 25
XLogP 2.48
PSA 44.791
NB_HD 1
NB_HA 5
fsp3 0.44
Lipinski(0=no;1=yes) 1

FDA
NDA 203567 (label) INN (EFINACONAZOLE) JUBLIA (BAUSCH) APPROVAL= AP YEAR= 2014 NEWMOLECULARENTITY
NDA 211827 (pdf not found) INN (EFINACONAZOLE) EFINACONAZOLE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2020
NDA 211851 (pdf not found) INN (EFINACONAZOLE) EFINACONAZOLE (PADAGIS US) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 211969 (pdf not found) INN (EFINACONAZOLE) EFINACONAZOLE (UMEDICA) APPROVAL= AP YEAR= 2021
NDA 212027 (pdf not found) INN (EFINACONAZOLE) EFINACONAZOLE (ALEMBIC PHARMACEUTICALS LIMITED) APPROVAL= TA YEAR= 2021
NDA 212066 (pdf not found) INN (EFINACONAZOLE) EFINACONAZOLE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 212169 (pdf not found) INN (EFINACONAZOLE) EFINACONAZOLE (LUPIN LTD) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 212178 (pdf not found) INN (EFINACONAZOLE) EFINACONAZOLE (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2022 DISCONTINUED