e-Drug3D

1709

M DIAZEPAM

INN
DIAZEPAM

cas 1088-11-5

CLASS

NERVOUS SYSTEM
ANXIOLYTIC
BENZODIAZEPINES
MUSCLE RELAXANTS
SEDATIVE

ROUTE (list)

ATC code

N05BA01

PK parameters

VD 29.2 LITER (65 KILOGRAM)
Cl 0.46 LITER / HOUR (65 KILOGRAM)
PPB 97 PERCENT
t1/2 46 HOUR

Target

TARGET GAMMA-AMINOBUTYRIC-ACID RECEPTOR

GABA A receptor alpha-5,beta-2,gamma-3 UNIPROT P31644 GABRA5

GABA-A receptor alpha-1,beta-2,gamma-2 UNIPROT P14867 GABRA1

Download SDF file

2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-

Formula:
C15H11ClN2O

Calculated chemical properties:

MW 270.71
NB_atoms 19
XLogP 3.13
PSA 39.99
NB_HD 1
NB_HA 3
fsp3 0.07
Lipinski(0=no;1=yes) 1

FDA
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