e-Drug3D

1705

M FLUTAMIDE

INN
FLUTAMIDE

cas 52806-53-8

CLASS

ANTINEOPLASTIC
ANTIANDROGENIC

ROUTE (list)

ATC code

L02BB01

PK parameters

Tmax 2 HOUR
PPB 93 PERCENT
t1/2 6 HOUR

Target

TARGET ANDROGEN RECEPTOR

PDB
4OH6 (CRYSTAL STRUCTURE OF T877A-AR-LBD BOUND WITH CO-REGULATOR PEPTIDE)

Download experimental 3D coordinates of HFT with added hydrogens

Androgen receptor UNIPROT P10275 AR

Download SDF file

Propanamide, 2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-

Formula:
C11H11F3N2O4

Calculated chemical properties:

MW 292.22
NB_atoms 20
XLogP 2.32
PSA 83.228
NB_HD 2
NB_HA 5
fsp3 0.36
Lipinski(0=no;1=yes) 1

FDA
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