e-Drug3D

1702

cas 36894-69-6

CLASS

CARDIOVASCULAR
ANTIHYPERTENSIVE
ANTIANGINAL
ADRENERGIC ALPHA ANTAGONISTS
ADRENERGIC BETA ANTAGONISTS
SYMPATHOLYTICS

ROUTE (list)

INJECTION ORAL INTRAVENOUS

PK parameters

F 25 PERCENT
Tmax 1.5 HOUR
VD 312 LITER (65 KILOGRAM)
Cl 128 LITER / HOUR (65 KILOGRAM)
PPB 50 PERCENT
t1/2 7 HOUR

MW 328.40
NB_atoms 24
XLogP 2.14
PSA 90.178
NB_HD 5
NB_HA 5
fsp3 0.32
Lipinski(0=no;1=yes) 1

FDA
NDA 019174 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; LABETALOL HYDROCHLORIDE) TRANDATE HCT (GLAXOSMITHKLINE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 018686 (pdf not found) INN (LABETALOL HYDROCHLORIDE) NORMODYNE (SCHERING) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 018687 (pdf not found) INN (LABETALOL HYDROCHLORIDE) NORMODYNE (SCHERING) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 018716 (pdf not found) INN (LABETALOL HYDROCHLORIDE) TRANDATE (ALVOGEN) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 019425 (pdf not found) INN (LABETALOL HYDROCHLORIDE) TRANDATE (SEBELA IRELAND LTD) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 019046 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; LABETALOL HYDROCHLORIDE) NORMOZIDE (SCHERING) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 074787 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (HERITAGE PHARMA) APPROVAL= AP YEAR= 1998
NDA 074989 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (TEVA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075113 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (SANDOZ) APPROVAL= AP YEAR= 1998
NDA 075133 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1998
NDA 075223 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (APOTHECON) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075215 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (ANDAS 5 HOLDING) APPROVAL= AP YEAR= 1999
NDA 075239 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1999
NDA 075240 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1999
NDA 075242 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075303 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 1999
NDA 075355 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (APOTHECON) APPROVAL= TA YEAR= 1999
NDA 075431 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 1999
NDA 075524 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 076051 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2002
NDA 079134 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (ONESOURCE SPECIALTY) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 090699 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (GLAND PHARMA LTD) APPROVAL= AP YEAR= 2012
NDA 200908 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 2012
NDA 207743 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2017
NDA 209603 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (APPCO) APPROVAL= AP YEAR= 2018
NDA 207863 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (HIBROW HLTHCARE) APPROVAL= AP YEAR= 2019
NDA 211325 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (CADILA PHARMS LTD) APPROVAL= AP YEAR= 2019
NDA 212990 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2020
NDA 213330 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE IN DEXTROSE (HIKMA) APPROVAL= AP YEAR= 2020
NDA 211953 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (RUBICON RESEARCH) APPROVAL= AP YEAR= 2021
NDA 214533 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (CAPLIN) APPROVAL= AP YEAR= 2021
NDA 212719 (pdf not found) INN (LABETALOL HYDROCHLORIDE) LABETALOL HYDROCHLORIDE (UNICHEM) APPROVAL= AP YEAR= 2022 DISCONTINUED