e-Drug3D

170

DYCLONINE

INN
DYCLONINE

cas 586-60-7

CLASS

NERVOUS SYSTEM
ANESTHETIC

ROUTE (list)

TOPICAL

ATC code

N01BX02
R02AD04

PK parameters

Target

PDB
7UGG (CRYO-EM STRUCTURE OF TRPV3 IN COMPLEX WITH THE ANESTHETIC DYCLONINE)

Ligand code = N8R (link to the list of PDB complexes)

Download experimental 3D coordinates of N8R with added hydrogens

DrugCentral

Sodium channel protein type 10 subunit alpha UNIPROT Q9Y5Y9 SCN10A

Download SDF file

1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one

Formula:
C18H27NO2

Calculated chemical properties:

MW 289.41
NB_atoms 21
XLogP 3.92
PSA 32.379
NB_HD 0
NB_HA 3
fsp3 0.61
Lipinski(0=no;1=yes) 1

FDA
NDA 009925 (pdf not found) INN (DYCLONINE HYDROCHLORIDE) DYCLONE (ASTRAZENECA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 200480 (pdf not found) INN (DYCLONINE HYDROCHLORIDE) DYCLOPRO (SEPTODONT) APPROVAL= AP YEAR= 2018