e-Drug3D
1684
cas 66004-77-1
CLASS
ANTIINFECTIVES
ANTI-HIV AGENTS
ANTIMETABOLITES
NUCLEOSIDE AND NUCLEOTIDE REVERSE TRANSCRIPTASE INHIBITORS
ROUTE (list)
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ATC code
J05AF03
PK parameters
TARGET HIV REVERSE TRANSCRIPTASE (GAG-POL)
DNA POLYMERASE-BETA
MITOCHONDRIAL DNA POLYMERASE-GAMMA
DNA POLYMERASE-BETA
MITOCHONDRIAL DNA POLYMERASE-GAMMA
PDB
4DQP (TERNARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT, DNA DUPLEX, AND DDCTP (PAIRED WITH DG OF TEMPLATE))
Ligand code = DCT (link to the list of PDB complexes)
Download experimental 3D coordinates of DCT with added hydrogens
Reverse transcriptase,RNaseH UNIPROT Q72547 pol
Formula:
C9H16N3O12P3
Calculated chemical properties:
MW 447.13
NB_atoms 27
XLogP -2.68
PSA 216.345
NB_HD 2
NB_HA 15
fsp3 0.56
Lipinski(0=no;1=yes) 0
NB_atoms 27
XLogP -2.68
PSA 216.345
NB_HD 2
NB_HA 15
fsp3 0.56
Lipinski(0=no;1=yes) 0
FDA
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