e-Drug3D

1683

M AMIFOSTINE

INN
AMIFOSTINE

cas 31098-42-7

CLASS

VARIOUS
RADIATION-PROTECTIVE AGENTS
REDUCTION OF THE CUMULATIVE RENAL TOXICITY OF CISPLATIN AND FOR THE REDUCTION OF THE TOXIC EFFECTS OF RADIATION ON NORMAL ORAL TISSUES
SCAVENGE REACTIVE OXYGEN SPECIES

ROUTE (list)

ATC code

V03AF05

PK parameters

t1/2 0.13 HOUR

Target

TARGET ALKALINE PHOSPHATASE

PDB
7NIZ (HUMAN 14-3-3 SIGMA IN COMPLEX WITH HUMAN ESTROGEN RECEPTOR ALPHA PEPTIDE AND LIGANDS FUSICOCCIN-A AND WR-1065)

Ligand code = UGH (link to the list of PDB complexes)

Download experimental 3D coordinates of UGH with added hydrogens

DrugCentral

Unknown

Download SDF file

Ethanethiol, 2-[(3-aminopropyl)amino]-

Formula:
C5H14N2S

Calculated chemical properties:

MW 134.25
NB_atoms 8
XLogP -0.15
PSA 39.888
NB_HD 3
NB_HA 2
fsp3 1.00
Lipinski(0=no;1=yes) 1

FDA
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