e-Drug3D

1640

M ENTECAVIR

INN
ENTECAVIR

cas 336608-44-7

CLASS

ANTIINFECTIVES
ANTIVIRAL
ANTI HEPATITIS B
GUANOSINE NUCLEOSIDE ANALOG

ROUTE (list)

ATC code

J05AF10

PK parameters

t1/2 15 HOUR

Target

TARGET HBV REVERSE TRANSCRIPTASE

Protein P UNIPROT Q9IF40 P

Download SDF file

Triphosphoric acid, P-[[(1R,3S,5S)-3-(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-5-hydroxy-2-methylenecyclopentyl]methyl] ester

Formula:
C12H18N5O12P3

Calculated chemical properties:

MW 513.19
NB_atoms 32
XLogP -3.00
PSA 252.017
NB_HD 4
NB_HA 17
fsp3 0.42
Lipinski(0=no;1=yes) 0

FDA
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