e-Drug3D

1639

M NELARABINE

INN
NELARABINE

cas 72490-81-4

CLASS

ANTINEOPLASTIC
TREATMENT OF PATIENTS WITH T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA AND T-CELL LYMPHOBLASTIC LYMPHOMA
FOR INCORPORATION INTO DE OXYRIBONUCLEIC ACID (DNA)

ROUTE (list)

ATC code

L01BB07

PK parameters

VD 80 LITER
Cl 16.9 LITER / HOUR
PPB 25 PERCENT
t1/2 3.2 HOUR

Target

TARGET DNA

DrugCentral

Unknown

Download SDF file

6H-Purin-6-one, 2-amino-1,9-dihydro-9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-beta-D-arabinofuranosyl]-

Formula:
C10H16N5O14P3

Calculated chemical properties:

MW 519.16
NB_atoms 32
XLogP -4.45
PSA 285.943
NB_HD 5
NB_HA 19
fsp3 0.50
Lipinski(0=no;1=yes) 0

FDA
-