e-Drug3D

163

METHYPRYLON

DISCONTINUED

INN
METHYPRYLON

cas 125-64-4

CLASS

NERVOUS SYSTEM
ANXIOLYTIC
SEDATIVES
HYPNOTICS

ROUTE (list)

ORAL

ATC code

N05CE02

PK parameters

VD 63 LITER (65 KILOGRAM)
Cl 0.77 LITER / HOUR (65 KILOGRAM)
t1/2 9.2 HOUR (PMID2866242)

Target

DrugCentral

GABA-A receptor alpha-1,beta-3,gamma-2 UNIPROT P14867 GABRA1

Download SDF file

3,3-diethyl-5-methylpiperidine-2,4-dione

Formula:
C10H17NO2

Calculated chemical properties:

MW 183.25
NB_atoms 13
XLogP 1.13
PSA 45.696
NB_HD 1
NB_HA 3
fsp3 0.80
Lipinski(0=no;1=yes) 1

FDA
NDA 009660 (pdf not found) INN (METHYPRYLON) NOLUDAR (ROCHE) APPROVAL= AP YEAR= 1955 NEWMOLECULARENTITY DISCONTINUED