e-Drug3D

1627

M SOFOSBUVIR

INN
SOFOSBUVIR

cas 1015073-42-3

CLASS

ANTIINFECTIVES
TREATMENT OF CHRONIC HEPATITIS C (CHC) INFECTION
HEPATITIS C VIRUS (HCV) NUCLEOTIDE ANALOG NS5B POLYMERASE INHIBITOR

ROUTE (list)

PK parameters

Tmax 3 HOUR
t1/2 27 HOUR

Target

TARGET HEPATITIS C VIRUS (HCV) NUCLEOTIDE ANALOG NS5B POLYMERASE

NS5B protein UNIPROT Q8JXU8 NS5B

Genome polyprotein UNIPROT P27958

Download SDF file

Uridine 5'-(tetrahydrogen triphosphate), 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)-

Formula:
C10H16FN2O14P3

Calculated chemical properties:

MW 496.13
NB_atoms 30
XLogP -3.66
PSA 232.995
NB_HD 2
NB_HA 16
fsp3 0.60
Lipinski(0=no;1=yes) 0

FDA
-