e-Drug3D

1606

cas 59-99-4

CLASS

NERVOUS SYSTEM
CHOLINESTERASE INHIBITOR
REVERSAL OF THE EFFECTS OF NON-DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS (NMBAS) AFTER SURGERY

ROUTE (list)

INTRAVENOUS INJECTION

PK parameters

VD 49 LITER (65 KILOGRAM)
Cl 34 LITER / HOUR (65 KILOGRAM)
PPB 20 PERCENT
t1/2 1.14 HOUR

MW 223.29
NB_atoms 16
XLogP 1.94
PSA 27.15
NB_HD 0
NB_HA 3
fsp3 0.42
Lipinski(0=no;1=yes) 1

FDA
NDA 204078 (label) INN (NEOSTIGMINE METHYLSULFATE) BLOXIVERZ (EXELA PHARMA) APPROVAL= AP YEAR= 2013
NDA 203629 (label) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2015
NDA 207042 (label) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (HIKMA) APPROVAL= AP YEAR= 2015
NDA 208405 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (PH HEALTH) APPROVAL= AP YEAR= 2017
NDA 209933 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (AMPHASTAR PHARMS INC) APPROVAL= AP YEAR= 2017
NDA 209182 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (AM REGENT) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 209135 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (DR REDDYS) APPROVAL= AP YEAR= 2018
NDA 210051 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (AMNEAL) APPROVAL= AP YEAR= 2018
NDA 210989 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (AMRING PHARMS) APPROVAL= AP YEAR= 2018
NDA 212512 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (BE PHARMS) APPROVAL= AP YEAR= 2019
NDA 212968 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (GLAND) APPROVAL= AP YEAR= 2019
NDA 212804 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (MEITHEAL) APPROVAL= AP YEAR= 2021
NDA 213074 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (CAPLIN) APPROVAL= AP YEAR= 2021
NDA 210652 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (ADAPTIS) APPROVAL= AP YEAR= 2021
NDA 216291 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (DR REDDYS) APPROVAL= AP YEAR= 2022
NDA 208230 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (AVET LIFESCIENCES) APPROVAL= AP YEAR= 2022
NDA 212627 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (UMEDICA) APPROVAL= AP YEAR= 2022
NDA 216206 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (HIKMA) APPROVAL= AP YEAR= 2022
NDA 216542 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (SAGENT PHARMS INC) APPROVAL= AP YEAR= 2023
NDA 216903 (label) INN (GLYCOPYRROLATE ; NEOSTIGMINE METHYLSULFATE) PREVDUO (AZURITY) APPROVAL= AP YEAR= 2023
NDA 213244 (pdf not found) INN (NEOSTIGMINE METHYLSULFATE) NEOSTIGMINE METHYLSULFATE (EUGIA PHARMA) APPROVAL= AP YEAR= 2023