e-Drug3D

1597

OSPEMIFENE

INN
OSPEMIFENE

cas 128607-22-7

CLASS

DYSPAREUNIA MENOPAUSE
ESTROGEN AGONIST/ANTAGONIST

ROUTE (list)

ORAL

ATC code

G03XC05

PK parameters

VD 448 LITER
Cl 9.16 LITER / HOUR
PPB 99 PERCENT
t1/2 26 HOUR

Solubility

INSOLUBLE IN WATER

Target

TARGET ESTROGEN RECEPTOR

DrugCentral

Estrogen receptor UNIPROT P03372 ESR1

Download SDF file

Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-

Formula:
C24H23ClO2

Calculated chemical properties:

MW 378.87
NB_atoms 27
XLogP 5.65
PSA 32.553
NB_HD 1
NB_HA 2
fsp3 0.17
Lipinski(0=no;1=yes) 0

FDA
NDA 203505 (label) INN (OSPEMIFENE) OSPHENA (DUCHESNAY) APPROVAL= AP YEAR= 2013
NDA 215574 (pdf not found) INN (OSPEMIFENE) OSPEMIFENE (HETERO LABS LTD V) APPROVAL= AP YEAR= 2024 DISCONTINUED