e-Drug3D

1591

M ENZALUTAMIDE

INN
ENZALUTAMIDE

cas 1242137-16-1

CLASS

ANTINEOPLASTIC
ANDROGEN RECEPTOR INHIBITOR
TREATMENT OF PATIENTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER
DECREASED PROLIFERATION AND INDUCED CELL DEATH

ROUTE (list)

ATC code

L02BB04

PK parameters

Cl 1.02 LITER / HOUR
PPB 95 PERCENT
t1/2 196 HOUR

Target

TARGET ANDROGEN RECEPTOR (AR)

DrugCentral

Androgen receptor UNIPROT P10275 AR

Download SDF file

Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro

Formula:
C20H14F4N4O2S

Calculated chemical properties:

MW 450.42
NB_atoms 31
XLogP 3.73
PSA 80.218
NB_HD 2
NB_HA 6
fsp3 0.20
Lipinski(0=no;1=yes) 1

FDA
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