e-Drug3D

1568

M DOLASETRON

INN
DOLASETRON

cas 127951-99-9

CLASS

METABOLISM
SEROTONIN 5HT3 ANTAGONIST
ANTIEMETIC

ROUTE (list)

ATC code

A04AA04

PK parameters

F 75 PERCENT
VD 377 LITER (65 KILOGRAM)
Cl 52 LITER / HOUR (65 KILOGRAM)
PPB 77 PERCENT
t1/2 8.1 HOUR

Target

TARGET 5-HYDROXYTRYPTAMINE 3 RECEPTOR

5-hydroxytryptamine receptor 3A UNIPROT P46098 HTR3A

Download SDF file

1H-Indole-3-carboxylic acid, octahydro-3-hydroxy-2,6-methano-2H-quinolizin-8-yl ester

Formula:
C19H22N2O3

Calculated chemical properties:

MW 326.39
NB_atoms 24
XLogP 2.31
PSA 58.341
NB_HD 2
NB_HA 5
fsp3 0.53
Lipinski(0=no;1=yes) 1

FDA
-