e-Drug3D

1561

M OSELTAMIVIR

INN
OSELTAMIVIR

cas 187227-45-8

CLASS

ANTIINFECTIVES
ANTIVIRAL
INFLUENZA NEURAMINIDASE INHIBITOR

ROUTE (list)

ATC code

J05AH02

PK parameters

VD 24.5 LITER
Cl 2.1 LITER / HOUR (EQN)
PPB 3 PERCENT
t1/2 8 HOUR

Target

TARGET NEURAMINIDASE

PDB
4QN7 (CRYSTAL STRUCTURE OF NEURAMNIDASE N7 COMPLEXED WITH OSELTAMIVIR)

Download experimental 3D coordinates of G39 with added hydrogens

Neuraminidase UNIPROT P03468

Neuraminidase UNIPROT P03474

Download SDF file

1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R,4R,5S)-

Formula:
C14H24N2O4

Calculated chemical properties:

MW 283.34
NB_atoms 20
XLogP -0.53
PSA 92.881
NB_HD 3
NB_HA 6
fsp3 0.71
Lipinski(0=no;1=yes) 1

FDA
-