e-Drug3D
1558
EFLORNITHINE
INN
EFLORNITHINE
cas 70052-12-9
CLASS
DERMATOLOGICALS
INHIBITOR OF ORNITHINE DECARBOXYLASE (ODC)
REDUCTION OF UNWANTED FACIAL HAIR IN WOMEN
ANTIPARASITIC
ROUTE (list)
INJECTION TOPICAL ORAL
PK parameters
t1/2 8 HOUR
TARGET ORNITHINE DECARBOXYLASE (ODC)
Ornithine decarboxylase UNIPROT P11926 ODC1
Ornithine decarboxylase UNIPROT Q9TZZ6
Formula:
C6H12F2N2O2
Calculated chemical properties:
MW 181.17
NB_atoms 12
XLogP -1.56
PSA 82.889
NB_HD 4
NB_HA 4
fsp3 0.83
Lipinski(0=no;1=yes) 1
NB_atoms 12
XLogP -1.56
PSA 82.889
NB_HD 4
NB_HA 4
fsp3 0.83
Lipinski(0=no;1=yes) 1
FDA
NDA 019879 (pdf not found) INN (EFLORNITHINE HYDROCHLORIDE) ORNIDYL (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1990 NEWMOLECULARENTITY DISCONTINUED
NDA 021145 (label) INN (EFLORNITHINE HYDROCHLORIDE) VANIQA (ABBVIE) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 215500 (label) INN (EFLORNITHINE HYDROCHLORIDE) IWILFIN (USWM) APPROVAL= AP YEAR= 2023
NDA 019879 (pdf not found) INN (EFLORNITHINE HYDROCHLORIDE) ORNIDYL (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1990 NEWMOLECULARENTITY DISCONTINUED
NDA 021145 (label) INN (EFLORNITHINE HYDROCHLORIDE) VANIQA (ABBVIE) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 215500 (label) INN (EFLORNITHINE HYDROCHLORIDE) IWILFIN (USWM) APPROVAL= AP YEAR= 2023