e-Drug3D

1546

M SAXAGLIPTIN

INN
SAXAGLIPTIN

cas 841302-24-7

CLASS

ANTIDIABETIC
DIPEPTIDYL-PEPTIDASE IV INHIBITOR
HYPOGLYCEMIC AGENTS
TYPE 2 DIABETES MELLITUS
METABOLISM
METABOLITE OF SAXAGLIPTIN IS ONE-HALF AS POTENT AS SAXAGLIPTIN AS DPP4 INHIBITOR

ROUTE (list)

ATC code

A10BD10
A10BD25
A10BH03
A10BD21

PK parameters

Cl 13.8 LITER / HOUR
PPB 0 PERCENT
t1/2 3.1 HOUR

Target

TARGET DIPEPTIDYL PEPTIDASE-4 (DPP-4)

DrugCentral

Dipeptidyl peptidase 4 UNIPROT P27487 DPP4

Download SDF file

2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-amino-2-(3,5-dihydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3S,5S)-

Formula:
C18H25N3O3

Calculated chemical properties:

MW 331.41
NB_atoms 24
XLogP 0.27
PSA 98.951
NB_HD 4
NB_HA 6
fsp3 0.89
Lipinski(0=no;1=yes) 1

FDA
-