e-Drug3D

1536

M AZILSARTAN KAMEDOXOMIL

INN
AZILSARTAN KAMEDOXOMIL

cas 147403-03-0

CLASS

CARDIOVASCULAR
ANTIHYPERTENSIVE
ANGIOTENSIN II RECEPTOR BLOCKER
SELECTIVE AT1 SUBTYPE ANGIOTENSIN II RECEPTOR ANTAGONIST

ROUTE (list)

PK parameters

F 60 PERCENT
Tmax 2.25 HOUR
VD 16 LITER
Cl 0.138 LITER / HOUR
PPB 99 PERCENT
t1/2 11 HOUR

Target

TARGET AT1 RECEPTOR

Type-1 angiotensin II receptor UNIPROT P30556 AGTR1

Download SDF file

1H-Benzimidazole-7-carboxylic acid, 1-[[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-

Formula:
C25H20N4O5

Calculated chemical properties:

MW 455.44
NB_atoms 34
XLogP 2.86
PSA 103.148
NB_HD 1
NB_HA 9
fsp3 0.12
Lipinski(0=no;1=yes) 1

FDA
-